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Protein Biochemistry
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MK-886
MK-886 from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
MK-886
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Description
A potent FLAP antagonist that prevents 5-LO activation in vivo; inhibits LT biosynthesis in leukocytes with an IC50 value of 2.5 nM
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
MK-886
Company
Cayman Chemical
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
21753
Format
A crystalline solid
Research Area
Immunology & Inflammation, Inflammatory Lipid Mediators, Leukotrienes, Lipid Biochemistry, Lipoxygenase Pathways
Molecular Weight
472.1
Quantity
10 mg
Purity
≥98%
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Skewing cPLA(2)α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis
Science signaling
July 11, 2023
Maus KD, Stephenson DJ, Macknight HP, Vu NT, Hoeferlin LA, Kim M, Diegelmann RF, Xie X, Chalfant CE.
at the following concentrations: 1.0 nM
5-HETE
(#
34210
), 1.0 nM
5-oxo-ETE
(#
34250
), 7.5 nM MK886 (#
21753
), 25 μM
Gue1654
(#
29686
), 100 nM physcion (
Santa Cruz
Biotech SC-205805). Cells were allowed to equilibrate
(2)
Vitamin D improves hepatic steatosis in NAFLD via regulation of fatty acid uptake and β-oxidation
Front Endocrinol (Lausanne)
March 22, 2023
Tingwan Du, Lian Xiang, Jingjing Zhang, Chunmei Yang, Wenxin Zhao, Jialu Li, Yong Zhou, Ling Ma
intervention: HFD + DMSO group (n=8), HFD + MK886 group (n=8), and HFD + MK886 + VD group (n=8). MK886 (No.
21753
,
Cayman
, USA) was dissolved in dimethyl sulfoxide (DMSO) (D8370-100 ml, Solarbio, China) with carboxymethylcellulose
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MK-886 from Cayman Chemical
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